Tecnobios

Artificial reproductive technology achievements for optimizing embryo quality

A. Borini, C. Lagalla, R. Sciajno, V. Distratis, M. A. Bonu, M. Cattoli and G. Coticchio (2004). Ann. N. Y. Acad. Sci. 1034: 252-261 (2004).

Abstract

Evaluation of morphological characteristics, to date, has been the most widely accepted method for the selection of embryos with higher developmental ability and optimization of the outcome of in vitro fertilization (IVF). Improvement in clinical results has also been pursued through attempts to generate embryos of high quality or to identify more reliable selection criteria. This work evaluates the possibility of improving embryo quality and subsequent IVF outcome in situations in which creation of supernumerary embryos is not allowed. Optimization of gamete selection and conditions of insemination, such as hormonal therapy to improve sperm quality of patients undergoing intracytoplasmic sperm injection treatment, use of power Doppler image for follicle selection, short coincubation of gametes during insemination, and use of a polscope for spindle detection, is described.

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